IMPACT OF PREGNANCY RELATED HORMONES ON DRUG METABOLIZING ENZYME AND TRANSPORT PROTEIN CONCENTRATIONS IN HUMAN HEPATOCYTES

Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes

Pregnancy alters the disposition and exposure to Hockey Protective - Helmet - Visors multiple drugs indicated for pregnancy-related complications.Previous in vitro studies have shown that pregnancy-related hormones (PRHs) alter the expression and function of certain cytochrome P450s (CYPs) in human hepatocytes.However, the impact of PRHs on hepatic

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Differential Susceptibility and Innate Immune Response of Aedes aegypti and Aedes albopictus to the Haitian Strain of the Mayaro Virus

Mayaro (MAYV) is an emerging arthropod-borne virus belonging to the Alphavirus genus of the Togaviridae family.Although forest-dwelling Haemagogus mosquitoes have been considered as its main vector, the virus has also been detected in circulating Aedes ssp mosquitoes.Here we assess the susceptibility of Aedes aegypti and Aedes albopictus to infecti

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Delusional Themes Across Affective and Non-Affective Psychoses

The current debate about the diagnostic significance of delusion revolves around two positions.The neurocognitive position conceives delusion as a non-specific, though polymorphic, symptom.The psychopathological position views features of delusion such as content and structure as having meaningful connections with diagnostic entities.This study aim

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Methodology for forecasting assessing the effectiveness of the asymmetric response of the armed forces of Ukraine to threats in the military sphere

A methodology for predictive evaluation of the effectiveness of an asymmetric response to modern threats is presented in the interests of ensuring an adequate level of military security of the state.In the context of the integrated use of military and non-military instruments (economic, political, information-psychological, etc.), there was a need

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